WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:
Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName #Gene EntrezGene Statistics
Huntington's disease 82 64764 4718 4698 4712 7381 5435 29796 1346 4711 4706 1339 25942 54539 522 4709 7386 517 4714 7419 4715 4731 4700 4720 10126 4704 6647 4717 1350 5441 27089 7417 514 7416 4707 513 515 6392 291 4694 9377 4722 7388 4713 4702 1340 1329 5440 4726 54205 4697 1327 1345 374291 1347 4724 4723 4695 4710 10476 4708 4728 10975 1537 1349 55967 4696 6667 516 3092 7384 23236 4716 5430 6390 5439 518 509 9167 1351 5434 4725 539 C=183;O=82;E=4.75;R=17.25;rawP=1.18e-79;adjP=1.85e-77
Oxidative phosphorylation 72 4718 4698 4712 7381 29796 1346 4711 4706 1339 54539 522 4709 7386 517 4714 4715 4731 4700 4720 155066 9550 4704 4717 1350 27089 514 4707 513 515 6392 4694 27068 9377 4722 7388 4713 4702 1340 1329 4726 4697 1327 1345 374291 1347 4724 4723 4695 4710 10476 4708 4728 1537 10975 1349 51606 55967 4696 516 10632 7384 9551 4716 6390 10063 51382 518 509 9167 1351 4725 539 C=132;O=72;E=3.43;R=21.00;rawP=3.65e-78;adjP=2.87e-76
Parkinson's disease 71 4718 4698 4712 7381 29796 1346 4711 4706 1339 54539 522 11315 4709 7386 517 4714 7419 4715 4731 4700 4720 4704 4717 1350 27089 7417 514 7416 4707 513 515 6392 291 4694 9377 4722 7388 4713 4702 1340 1329 4726 54205 4697 1327 1345 374291 1347 4724 4723 4695 4710 10476 4708 4728 10975 1537 1349 7314 55967 4696 516 7384 4716 6390 518 509 9167 1351 4725 539 C=130;O=71;E=3.38;R=21.03;rawP=3.83e-77;adjP=2.00e-75
Alzheimer's disease 72 4718 4698 4712 7381 29796 1346 4711 4706 1339 54539 522 4709 7386 805 517 4714 4715 4731 4700 4720 8883 4704 4717 2597 1350 27089 514 4707 513 515 6392 4694 9377 4722 7388 4713 4702 1340 1329 23621 4726 3028 54205 4697 1327 1345 374291 1347 4724 4723 4695 4710 10476 4708 4728 10975 1537 1349 55967 4696 516 801 7384 23236 4716 6390 518 509 9167 1351 4725 539 C=167;O=72;E=4.34;R=16.60;rawP=1.69e-68;adjP=6.63e-67
Metabolic pathways 153 79717 317749 4712 7381 5435 29796 2746 1339 2639 51251 522 587 10841 55902 517 4714 51102 231 8801 4715 4731 54995 4700 4720 55454 5160 35 4717 2271 51809 5162 80142 515 7263 2531 226 9377 4722 7388 55568 4702 1340 1158 9942 80025 1329 5440 4726 3028 1327 4697 54344 1345 122622 374291 4724 10476 4708 2027 10975 1152 1537 51606 51805 56052 337876 516 9489 5095 3421 2629 1635 23236 5213 4716 10901 10063 6390 159 2875 283871 5439 509 26290 5434 27349 4190 2821 84532 4698 4718 8802 8382 4191 64131 4711 4706 3418 1160 2132 4709 80146 7386 1854 6888 326625 155066 9550 84693 4704 2597 1350 7390 5441 27089 514 4707 513 6392 9380 51181 4694 4713 22934 2710 11019 30 10682 4723 883 4695 4710 5860 51227 4728 1349 4696 56953 3945 10632 1892 7384 9551 5430 51382 3033 518 5730 1351 4725 3420 112483 539 C=1130;O=153;E=29.35;R=5.21;rawP=1.73e-64;adjP=5.43e-63
Cardiac muscle contraction 25 1329 1350 7137 7170 7381 27089 29796 1346 1327 7384 1339 1345 55799 1347 7386 783 9167 1351 9377 7388 10975 1537 1349 1340 4634 C=77;O=25;E=2.00;R=12.50;rawP=5.67e-21;adjP=1.48e-19
Proteasome 17 5689 5693 5684 5692 5702 5695 5682 5685 5704 5719 5706 7979 5701 5705 9861 5700 5694 C=44;O=17;E=1.14;R=14.88;rawP=3.50e-16;adjP=7.85e-15
Citrate cycle (TCA cycle) 12 6390 5160 8802 4191 3421 2271 8801 4190 3418 3420 5162 6392 C=30;O=12;E=0.78;R=15.40;rawP=4.99e-12;adjP=9.79e-11
Ubiquitin mediated proteolysis 18 6923 9978 7428 9039 8450 7319 8697 11060 4193 997 51529 10393 51619 6500 7320 7321 9040 4281 C=135;O=18;E=3.51;R=5.13;rawP=1.53e-08;adjP=2.67e-07
Pyruvate metabolism 10 5160 9380 55902 4191 231 2739 4190 84532 5162 3945 C=40;O=10;E=1.04;R=9.63;rawP=5.60e-08;adjP=8.79e-07


WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).